Population Substructure and Control Selection in Genome-Wide Association Studies

Determination of the relevance of both demanding classical epidemiologic criteria for control selection and robust handling of population stratification (PS) represents a major challenge in the design and analysis of genome-wide association studies (GWAS). Empirical data from two GWAS in European Am...

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Autores principales: Yu, Kai, Wang, Zhaoming, Li, Qizhai, Wacholder, Sholom, Hunter, David J., Hoover, Robert N., Chanock, Stephen, Thomas, Gilles
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2432498/
https://ncbi.nlm.nih.gov/pubmed/18596976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002551
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