PD-1 Controls Tonic Signaling and Lymphopenia-Induced Proliferation of T Lymphocytes

Recovery of the T lymphocyte compartment within a lymphopenic host by lymphopenia-induced proliferation (LIP) is regulated by inter- and intraclonal competition for limited resources, including homeostatic cytokines and peptide:MHC (pMHC) complexes with which the TCR can interact at least weakly to...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Ellestad, Kristofor K., Lin, Jiaxin, Boon, Louis, Anderson, Colin C.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643416/
https://ncbi.nlm.nih.gov/pubmed/29075267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01289
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