Stability of Chimerism in Non-Obese Diabetic Mice Achieved By Rapid T Cell Depletion Is Associated With High Levels of Donor Cells Very Early After Transplant

Stable mixed hematopoietic chimerism is a robust method for inducing donor-specific tolerance with the potential to prevent rejection of donor islets in recipients with autoimmune type-1 diabetes. However, with reduced intensity conditioning, fully allogeneic chimerism in a tolerance resistant autoi...

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Vydáno v:Front Immunol
Hlavní autoři: Lin, Jiaxin, Chan, William F. N., Boon, Louis, Anderson, Colin C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928230/
https://ncbi.nlm.nih.gov/pubmed/29740442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00837
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