Desensitization using imlifidase and EndoS enables chimerism induction in allosensitized recipient mice

Mixed hematopoietic chimerism induction as a way to foster tolerance to donor organs in recipients who have been sensitized to donor antigens is challenging. Donor‐specific antibodies (DSA) are a dominant barrier toward successful donor bone marrow engraftment. Although desensitization methods are r...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Transplant
Hauptverfasser: Lin, Jiaxin, Boon, Louis, Bockermann, Robert, Robertson, Anna‐Karin, Kjellman, Christian, Anderson, Colin C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
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ORIGINAL ARTICLES
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496317/
https://ncbi.nlm.nih.gov/pubmed/32185855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.15851
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