ロード中...
A Histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1
RasGRPs are guanine nucleotide exchange factors that are specific for Ras or Rap, and are important regulators of cellular signaling. Aberrant expression or mutation of RasGRPs results in disease. An analysis of RasGRP1 SNP variants led to the conclusion that the charge of His 212 in RasGRP1 alters...
保存先:
| 出版年: | eLife |
|---|---|
| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2017
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5643099/ https://ncbi.nlm.nih.gov/pubmed/28952923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.29002 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|