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Ischemic Cerebroprotection Conferred by Myeloid Lineage-restricted or Global CD39 Transgene Expression

BACKGROUND: Cerebral tissue damage after an ischemic event can be exacerbated by inflammation and thrombosis. Elevated extracellular ATP and ADP levels are associated with cellular injury, inflammation and thrombosis. Ectonucleoside triphosphate diphosphohydrolase-1 (CD39), an enzyme expressed on th...

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Detalhes bibliográficos
Publicado no:Circulation
Main Authors: Baek, Amy E., Sutton, Nadia R., Petrovic-Djergovic, Danica, Liao, Hui, Ray, Jessica, Park, Joan, Kanthi, Yogendra, Pinsky, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643044/
https://ncbi.nlm.nih.gov/pubmed/28377485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.116.023301
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