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Regulation of ecto-apyrase CD39 (ENTPD1) expression by phosphodiesterase III (PDE3)

The ectoenzyme CD39 suppresses thrombosis and inflammation by suppressing ATP and ADP to AMP. However, mechanisms of CD39 transcriptional and post-translational regulation are not well known. Here we show that CD39 levels are modulated by inhibition of phosphodiesterase 3 (PDE3). RAW macrophages and...

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Hlavní autoři: Baek, Amy E., Kanthi, Yogendra, Sutton, Nadia R., Liao, Hui, Pinsky, David J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804755/
https://ncbi.nlm.nih.gov/pubmed/23901069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-234625
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