cAMP/CREB-mediated Transcriptional Regulation of Ectonucleoside Triphosphate Diphosphohydrolase 1 (CD39) Expression

CD39 is a transmembrane enzyme that inhibits platelet reactivity and inflammation by phosphohydrolyzing ATP and ADP to AMP. Cyclic AMP (cAMP), an essential second messenger, is particularly important in regulating genes controlling vascular homeostasis. These experiments test the hypothesis that cAM...

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Detalhes bibliográficos
Main Authors: Liao, Hui, Hyman, Matthew C., Baek, Amy E., Fukase, Keigo, Pinsky, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863166/
https://ncbi.nlm.nih.gov/pubmed/20178980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.116905
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