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Association and clinical utility of NAT2 in the prediction of isoniazid-induced liver injury in Singaporean patients
BACKGROUND AND AIMS: Isoniazid (INH) is part of the first-line-therapy for tuberculosis (TB) but can cause drug-induced liver injury (DILI). Several candidate single nucleotide polymorphisms (SNPs) have been previously identified but the clinical utility of these SNPs in the prediction of INH-DILI r...
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| Pubblicato in: | PLoS One |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5642896/ https://ncbi.nlm.nih.gov/pubmed/29036176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186200 |
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