Prevention of isoniazid toxicity by NAT2 genotyping in Senegalese tuberculosis patients

Isoniazid (INH), recommended by WHO (World Health Organization) in the treatment of tuberculosis (TB), is metabolized primarily by the genetically polymorphic N-acetyltransferase 2 (NAT2) enzyme. The human population is divided into three different phenotypic groups according to acetylation rate: sl...

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Detalhes bibliográficos
Publicado no:Toxicol Rep
Main Authors: Toure, A., Cabral, M., Niang, A., Diop, C., Garat, A., Humbert, L., Fall, M., Diouf, A., Broly, F., Lhermitte, M., Allorge, D.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5616082/
https://ncbi.nlm.nih.gov/pubmed/28959610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2016.10.004
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