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Prevention of isoniazid toxicity by NAT2 genotyping in Senegalese tuberculosis patients

Isoniazid (INH), recommended by WHO (World Health Organization) in the treatment of tuberculosis (TB), is metabolized primarily by the genetically polymorphic N-acetyltransferase 2 (NAT2) enzyme. The human population is divided into three different phenotypic groups according to acetylation rate: sl...

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Bibliografische gegevens
Gepubliceerd in:Toxicol Rep
Hoofdauteurs: Toure, A., Cabral, M., Niang, A., Diop, C., Garat, A., Humbert, L., Fall, M., Diouf, A., Broly, F., Lhermitte, M., Allorge, D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5616082/
https://ncbi.nlm.nih.gov/pubmed/28959610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2016.10.004
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