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Prevention of isoniazid toxicity by NAT2 genotyping in Senegalese tuberculosis patients

Isoniazid (INH), recommended by WHO (World Health Organization) in the treatment of tuberculosis (TB), is metabolized primarily by the genetically polymorphic N-acetyltransferase 2 (NAT2) enzyme. The human population is divided into three different phenotypic groups according to acetylation rate: sl...

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Bibliografske podrobnosti
izdano v:Toxicol Rep
Main Authors: Toure, A., Cabral, M., Niang, A., Diop, C., Garat, A., Humbert, L., Fall, M., Diouf, A., Broly, F., Lhermitte, M., Allorge, D.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5616082/
https://ncbi.nlm.nih.gov/pubmed/28959610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2016.10.004
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