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Prevention of isoniazid toxicity by NAT2 genotyping in Senegalese tuberculosis patients

Isoniazid (INH), recommended by WHO (World Health Organization) in the treatment of tuberculosis (TB), is metabolized primarily by the genetically polymorphic N-acetyltransferase 2 (NAT2) enzyme. The human population is divided into three different phenotypic groups according to acetylation rate: sl...

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Bibliografski detalji
Izdano u:Toxicol Rep
Glavni autori: Toure, A., Cabral, M., Niang, A., Diop, C., Garat, A., Humbert, L., Fall, M., Diouf, A., Broly, F., Lhermitte, M., Allorge, D.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5616082/
https://ncbi.nlm.nih.gov/pubmed/28959610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2016.10.004
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