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The Pharmacogenetics of NAT2 Enzyme Maturation in Perinatally HIV Exposed Infants Receiving Isoniazid

The roles of the NAT2 genotype and enzyme maturation on isoniazid pharmacokinetics were investigated in South African infants with perinatal HIV exposure enrolled in a randomized, double-blind, controlled trial of isoniazid for prevention of tuberculosis disease and latent infection. Plasma concentr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhu, Rui, Kiser, Jennifer J., Seifart, Heiner I., Werely, Cedric J., Mitchell, Charles D., D’Argenio, David Z., Fletcher, Courtney V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182303/
https://ncbi.nlm.nih.gov/pubmed/21558457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0091270011402826
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