Isoniazid pharmacokinetics, pharmacodynamics and dosing in South African infants

AIMS: There are limited data on isoniazid (INH) pharmacokinetics in infants and young children and, therefore, uncertainty on appropriate dosing. METHODS: Pharmacokinetic data were obtained from perinatally HIV-exposed South African infants ages 3–24 months receiving INH 10–20 mg/kg/day orally for M...

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Main Authors: Kiser, Jennifer J., Zhu, Rui, D’Argenio, David Z., Cotton, Mark F., Bobat, Raziya, McSherry, George D., Madhi, Shabir A, Carey, Vincent J., Seifart, Heiner I., Werely, Cedric J., Fletcher, Courtney V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397663/
https://ncbi.nlm.nih.gov/pubmed/22695364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FTD.0b013e31825c4bc3
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