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Miscoding-induced stalling of substrate translocation on the bacterial ribosome
Directional transit of the ribosome along the messenger RNA (mRNA) template is a key determinant of the rate and processivity of protein synthesis. Imaging of the multistep translocation mechanism using single-molecule FRET has led to the hypothesis that substrate movements relative to the ribosome...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5642701/ https://ncbi.nlm.nih.gov/pubmed/28973849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1707539114 |
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