Acrolein induces mtDNA damages, mitochondrial fission and mitophagy in human lung cells

Acrolein (Acr), a highly reactive unsaturated aldehyde, can cause various lung diseases including asthma, chronic obstructive pulmonary disease (COPD), and lung cancer. We have found that Acr can damage not only genomic DNA but also DNA repair proteins causing repair dysfunction and enhancing cells’...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Wang, Hsiang-Tsui, Lin, Jing-Heng, Yang, Chun-Hsiang, Haung, Chun-Hao, Weng, Ching-Wen, Maan-Yuh Lin, Anya, Lo, Yu-Li, Chen, Wei-Shen, Tang, Moon-Shong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2017
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642564/
https://ncbi.nlm.nih.gov/pubmed/29050289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19710
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