Acrolein induces mtDNA damages, mitochondrial fission and mitophagy in human lung cells

Acrolein (Acr), a highly reactive unsaturated aldehyde, can cause various lung diseases including asthma, chronic obstructive pulmonary disease (COPD), and lung cancer. We have found that Acr can damage not only genomic DNA but also DNA repair proteins causing repair dysfunction and enhancing cells’...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Wang, Hsiang-Tsui, Lin, Jing-Heng, Yang, Chun-Hsiang, Haung, Chun-Hao, Weng, Ching-Wen, Maan-Yuh Lin, Anya, Lo, Yu-Li, Chen, Wei-Shen, Tang, Moon-Shong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2017
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642564/
https://ncbi.nlm.nih.gov/pubmed/29050289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19710
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