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Neuroprotective effect of selumetinib on acrolein-induced neurotoxicity
Abnormal accumulation of acrolein, an α, β unsaturated aldehyde has been reported as one pathological cause of the CNS neurodegenerative diseases. In the present study, the neuroprotective effect of selumetinib (a MEK–ERK inhibitor) on acrolein-induced neurotoxicity was investigated in vitro using p...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8203693/ https://ncbi.nlm.nih.gov/pubmed/34127699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-91507-6 |
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