HTLV-1 viral oncogene HBZ induces osteolytic bone disease in transgenic mice

Adult T-cell leukemia/lymphoma (ATL) is an aggressive T cell malignancy that occurs in HTLV-1 infected patients. Most ATL patients develop osteolytic lesions and hypercalcemia of malignancy, causing severe skeletal related complications and reduced overall survival. The HTLV-1 virus encodes 2 viral...

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Vydáno v:Oncotarget
Hlavní autoři: Esser, Alison K., Rauch, Daniel A., Xiang, Jingyu, Harding, John C., Kohart, Nicole A., Ross, Michael H., Su, Xinming, Wu, Kevin, Huey, Devra, Xu, Yalin, Vij, Kiran, Green, Patrick L., Rosol, Thomas J., Niewiesk, Stefan, Ratner, Lee, Weilbaecher, Katherine N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Priority Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642476/
https://ncbi.nlm.nih.gov/pubmed/29050201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20565
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