In Vivo Tumorigenesis, Osteolytic Sarcomas, and Tumorigenic Cell Lines from Transgenic Mice Expressing the Human T-Lymphotropic Virus Type 1 (HTLV-1) Tax Viral Oncogene

Human T-lymphotropic virus type 1 (HTLV-1) causes adult T-cell leukemia, a disease commonly associated with hypercalcemia and osteolysis. There is no effective treatment for HTLV-1, and the osteolytic mechanisms are not fully understood. Mice expressing the HTLV-1 oncogene Tax, driven by the human g...

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Veröffentlicht in:Am J Pathol
Hauptverfasser: Lanigan, Lisa G., Hildreth, Blake E., Dirksen, Wessel P., Simmons, Jessica K., Martin, Chelsea K., Werbeck, Jillian L., Thudi, Nandu K., Papenfuss, Tracey L., Boyaka, Prosper N., Toribio, Ramiro E., Ward, Jerrold M., Weilbaecher, Katherine N., Rosol, Thomas J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2021
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Regular Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863134/
https://ncbi.nlm.nih.gov/pubmed/33181139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2020.10.014
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