In Vivo Tumorigenesis, Osteolytic Sarcomas, and Tumorigenic Cell Lines from Transgenic Mice Expressing the Human T-Lymphotropic Virus Type 1 (HTLV-1) Tax Viral Oncogene

Human T-lymphotropic virus type 1 (HTLV-1) causes adult T-cell leukemia, a disease commonly associated with hypercalcemia and osteolysis. There is no effective treatment for HTLV-1, and the osteolytic mechanisms are not fully understood. Mice expressing the HTLV-1 oncogene Tax, driven by the human g...

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Udgivet i:Am J Pathol
Main Authors: Lanigan, Lisa G., Hildreth, Blake E., Dirksen, Wessel P., Simmons, Jessica K., Martin, Chelsea K., Werbeck, Jillian L., Thudi, Nandu K., Papenfuss, Tracey L., Boyaka, Prosper N., Toribio, Ramiro E., Ward, Jerrold M., Weilbaecher, Katherine N., Rosol, Thomas J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2021
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7863134/
https://ncbi.nlm.nih.gov/pubmed/33181139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2020.10.014
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