Mutant IDH1 and Thrombosis in Gliomas

Mutant isocitrate dehydrogenase 1 (IDH1) is common in gliomas, and produces D-2-hydroxyglutarate (D-2-HG). The full effects of IDH1 mutations on glioma biology and tumor microenvironment are unknown. We analyzed a discovery cohort of 169 World Health Organization (WHO) grade II-IV gliomas, followed...

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Detaylı Bibliyografya
Yayımlandı:Acta Neuropathol
Asıl Yazarlar: Unruh, Dusten, Schwarze, Steven R., Khoury, Laith, Thomas, Cheddhi, Wu, Meijing, Chen, Li, Chen, Rui, Liu, Yinxing, Schwartz, Margaret A., Amidei, Christina, Kumthekar, Priya, Benjamin, Carolina G., Song, Kristine, Dawson, Caleb, Rispoli, Joanne M., Fatterpekar, Girish, Golfinos, John G., Kondziolka, Douglas, Karajannis, Matthias, Pacione, Donato, Zagzag, David, McIntyre, Thomas, Snuderl, Matija, Horbinski, Craig
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640980/
https://ncbi.nlm.nih.gov/pubmed/27664011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-016-1620-7
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