Mutant IDH1 and Thrombosis in Gliomas

Mutant isocitrate dehydrogenase 1 (IDH1) is common in gliomas, and produces D-2-hydroxyglutarate (D-2-HG). The full effects of IDH1 mutations on glioma biology and tumor microenvironment are unknown. We analyzed a discovery cohort of 169 World Health Organization (WHO) grade II-IV gliomas, followed...

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書誌詳細
出版年:Acta Neuropathol
主要な著者: Unruh, Dusten, Schwarze, Steven R., Khoury, Laith, Thomas, Cheddhi, Wu, Meijing, Chen, Li, Chen, Rui, Liu, Yinxing, Schwartz, Margaret A., Amidei, Christina, Kumthekar, Priya, Benjamin, Carolina G., Song, Kristine, Dawson, Caleb, Rispoli, Joanne M., Fatterpekar, Girish, Golfinos, John G., Kondziolka, Douglas, Karajannis, Matthias, Pacione, Donato, Zagzag, David, McIntyre, Thomas, Snuderl, Matija, Horbinski, Craig
フォーマット: Artigo
言語:Inglês
出版事項: 2016
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Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640980/
https://ncbi.nlm.nih.gov/pubmed/27664011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-016-1620-7
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