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Mutant IDH1 and Thrombosis in Gliomas

Mutant isocitrate dehydrogenase 1 (IDH1) is common in gliomas, and produces D-2-hydroxyglutarate (D-2-HG). The full effects of IDH1 mutations on glioma biology and tumor microenvironment are unknown. We analyzed a discovery cohort of 169 World Health Organization (WHO) grade II-IV gliomas, followed...

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Xehetasun bibliografikoak
Argitaratua izan da:Acta Neuropathol
Egile Nagusiak: Unruh, Dusten, Schwarze, Steven R., Khoury, Laith, Thomas, Cheddhi, Wu, Meijing, Chen, Li, Chen, Rui, Liu, Yinxing, Schwartz, Margaret A., Amidei, Christina, Kumthekar, Priya, Benjamin, Carolina G., Song, Kristine, Dawson, Caleb, Rispoli, Joanne M., Fatterpekar, Girish, Golfinos, John G., Kondziolka, Douglas, Karajannis, Matthias, Pacione, Donato, Zagzag, David, McIntyre, Thomas, Snuderl, Matija, Horbinski, Craig
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640980/
https://ncbi.nlm.nih.gov/pubmed/27664011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-016-1620-7
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