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Molecular mechanism of synergy between the antimicrobial peptides PGLa and magainin 2
PGLa and magainin 2 (MAG2) are amphiphilic α-helical membranolytic peptides from frog skin with known synergistic antimicrobial activity. By systematically mutating residues in the two peptides it was possible to identify the ones crucial for the synergy, as monitored by biological assays, fluoresce...
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| Publicado en: | Sci Rep |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5640672/ https://ncbi.nlm.nih.gov/pubmed/29030606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12599-7 |
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