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Molecular mechanism of synergy between the antimicrobial peptides PGLa and magainin 2
PGLa and magainin 2 (MAG2) are amphiphilic α-helical membranolytic peptides from frog skin with known synergistic antimicrobial activity. By systematically mutating residues in the two peptides it was possible to identify the ones crucial for the synergy, as monitored by biological assays, fluoresce...
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| Опубликовано в: : | Sci Rep |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5640672/ https://ncbi.nlm.nih.gov/pubmed/29030606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12599-7 |
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