Nesprin-1α-Dependent Microtubule Nucleation from the Nuclear Envelope via Akap450 Is Necessary for Nuclear Positioning in Muscle Cells

The nucleus is the main microtubule-organizing center (MTOC) in muscle cells due to the accumulation of centrosomal proteins and microtubule (MT) nucleation activity at the nuclear envelope (NE) [1, 2, 3, 4]. The relocalization of centrosomal proteins, including Pericentrin, Pcm1, and γ-tubulin, dep...

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Publicat a:Curr Biol
Autors principals: Gimpel, Petra, Lee, Yin Loon, Sobota, Radoslaw M., Calvi, Alessandra, Koullourou, Victoria, Patel, Rutti, Mamchaoui, Kamel, Nédélec, François, Shackleton, Sue, Schmoranzer, Jan, Burke, Brian, Cadot, Bruno, Gomes, Edgar R.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640514/
https://ncbi.nlm.nih.gov/pubmed/28966089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2017.08.031
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