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Nesprin 1 is critical for nuclear positioning and anchorage

Nesprin 1 is an outer nuclear membrane protein that is thought to link the nucleus to the actin cytoskeleton. Recent data suggest that mutations in Nesprin 1 may also be involved in the pathogenesis of Emery-Dreifuss muscular dystrophy. To investigate the function of Nesprin 1 in vivo, we generated...

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Detalhes bibliográficos
Main Authors: Zhang, Jianlin, Felder, Amanda, Liu, Yujie, Guo, Ling T., Lange, Stephan, Dalton, Nancy D., Gu, Yusu, Peterson, Kirk L., Mizisin, Andrew P., Shelton, G. Diane, Lieber, Richard L., Chen, Ju
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796894/
https://ncbi.nlm.nih.gov/pubmed/19864491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp499
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