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Disruption of both nesprin 1 and desmin results in nuclear anchorage defects and fibrosis in skeletal muscle

Proper localization and anchorage of nuclei within skeletal muscle is critical for cellular function. Alterations in nuclear anchoring proteins modify a number of cellular functions including mechanotransduction, nuclear localization, chromatin positioning/compaction and overall organ function. In s...

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Detalhes bibliográficos
Main Authors: Chapman, Mark A., Zhang, Jianlin, Banerjee, Indroneal, Guo, Ling T., Zhang, Zhiwei, Shelton, G. Diane, Ouyang, Kunfu, Lieber, Richard L., Chen, Ju
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4204769/
https://ncbi.nlm.nih.gov/pubmed/24943590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu310
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