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The Muscle Ankyrin Repeat Proteins CARP, Ankrd2, and DARP Are Not Essential for Normal Cardiac Development and Function at Basal Conditions and in Response to Pressure Overload

Ankrd1/CARP, Ankrd2/Arpp, and Ankrd23/DARP belong to a family of stress inducible ankyrin repeat proteins expressed in striated muscle (MARPs). The MARPs are homologous in structure and localized in the nucleus where they negatively regulate gene expression as well as in the sarcomeric I-band, where...

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Autors principals: Bang, Marie-Louise, Gu, Yusu, Dalton, Nancy D., Peterson, Kirk L., Chien, Kenneth R., Chen, Ju
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988038/
https://ncbi.nlm.nih.gov/pubmed/24736439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093638
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