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Microtubule nucleation at the cis-side of the Golgi apparatus requires AKAP450 and GM130

We report that microtubule (MT) nucleation at the Golgi apparatus requires AKAP450, a centrosomal γ-TuRC-interacting protein that also forms a distinct network associated with the Golgi. Depletion of AKAP450 abolished MT nucleation at the Golgi, whereas depletion of the cis-Golgi protein GM130 led t...

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Bibliografiske detaljer
Main Authors: Rivero, Sabrina, Cardenas, Jesus, Bornens, Michel, Rios, Rosa M
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683699/
https://ncbi.nlm.nih.gov/pubmed/19242490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.47
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