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Lipophagy maintains energy homeostasis in the kidney proximal tubule during prolonged starvation

Macroautophagy/autophagy is a self-degradation process that combats starvation. Lipids are the main energy source in kidney proximal tubular cells (PTCs). During starvation, PTCs increase fatty acid (FA) uptake, form intracellular lipid droplets (LDs), and hydrolyze them for use. The involvement of...

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Bibliographische Detailangaben
Veröffentlicht in:Autophagy
Hauptverfasser: Minami, Satoshi, Yamamoto, Takeshi, Takabatake, Yoshitsugu, Takahashi, Atsushi, Namba, Tomoko, Matsuda, Jun, Kimura, Tomonori, Kaimori, Jun-ya, Matsui, Isao, Hamano, Takayuki, Takeda, Hiroaki, Takahashi, Masatomo, Izumi, Yoshihiro, Bamba, Takeshi, Matsusaka, Taiji, Niimura, Fumio, Isaka, Yoshitaka
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640178/
https://ncbi.nlm.nih.gov/pubmed/28813167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1341464
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