The DNA Sensing Aim2 Inflammasome Controls Radiation Induced Cell death and Tissue Injury

Acute exposure to ionizing radiation induces massive cell death and severe damage to tissues containing actively proliferating cells, including bone marrow and the gastrointestinal tract. However, the cellular and molecular mechanisms underlying this pathology remain controversial. Herein, we show t...

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Udgivet i:Science
Main Authors: Hu, Bo, Jin, Chengcheng, Li, Hua-Bing, Tong, Jiyu, Ouyang, Xinshou, Cetinbas, Naniye Malli, Zhu, Shu, Strowig, Till, Lam, Fred C., Zhao, Chen, Henao-Mejia, Jorge, Yilmaz, Omer, Fitzgerald, Katherine A., Eisenbarth, Stephanie C., Elinav, Eran, Flavell, Richard A.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640175/
https://ncbi.nlm.nih.gov/pubmed/27846608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf7532
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