The DNA Sensing Aim2 Inflammasome Controls Radiation Induced Cell death and Tissue Injury

Acute exposure to ionizing radiation induces massive cell death and severe damage to tissues containing actively proliferating cells, including bone marrow and the gastrointestinal tract. However, the cellular and molecular mechanisms underlying this pathology remain controversial. Herein, we show t...

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Publicado no:Science
Main Authors: Hu, Bo, Jin, Chengcheng, Li, Hua-Bing, Tong, Jiyu, Ouyang, Xinshou, Cetinbas, Naniye Malli, Zhu, Shu, Strowig, Till, Lam, Fred C., Zhao, Chen, Henao-Mejia, Jorge, Yilmaz, Omer, Fitzgerald, Katherine A., Eisenbarth, Stephanie C., Elinav, Eran, Flavell, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640175/
https://ncbi.nlm.nih.gov/pubmed/27846608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf7532
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