Top-Down Inhibition of BMP Signaling Enables Robust Induction of hPSCs Into Neural Crest in Fully Defined, Xeno-free Conditions

Defects in neural crest development have been implicated in many human disorders, but information about human neural crest formation mostly depends on extrapolation from model organisms. Human pluripotent stem cells (hPSCs) can be differentiated into in vitro counterparts of the neural crest, and so...

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Publicat a:Stem Cell Reports
Autors principals: Hackland, James O.S., Frith, Tom J.R., Thompson, Oliver, Marin Navarro, Ana, Garcia-Castro, Martin I., Unger, Christian, Andrews, Peter W.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2017
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Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5639211/
https://ncbi.nlm.nih.gov/pubmed/28919261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.08.008
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