Top-Down Inhibition of BMP Signaling Enables Robust Induction of hPSCs Into Neural Crest in Fully Defined, Xeno-free Conditions

Defects in neural crest development have been implicated in many human disorders, but information about human neural crest formation mostly depends on extrapolation from model organisms. Human pluripotent stem cells (hPSCs) can be differentiated into in vitro counterparts of the neural crest, and so...

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Bibliografiske detaljer
Udgivet i:Stem Cell Reports
Main Authors: Hackland, James O.S., Frith, Tom J.R., Thompson, Oliver, Marin Navarro, Ana, Garcia-Castro, Martin I., Unger, Christian, Andrews, Peter W.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5639211/
https://ncbi.nlm.nih.gov/pubmed/28919261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.08.008
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