Top-Down Inhibition of BMP Signaling Enables Robust Induction of hPSCs Into Neural Crest in Fully Defined, Xeno-free Conditions

Defects in neural crest development have been implicated in many human disorders, but information about human neural crest formation mostly depends on extrapolation from model organisms. Human pluripotent stem cells (hPSCs) can be differentiated into in vitro counterparts of the neural crest, and so...

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Bibliografski detalji
Izdano u:Stem Cell Reports
Glavni autori: Hackland, James O.S., Frith, Tom J.R., Thompson, Oliver, Marin Navarro, Ana, Garcia-Castro, Martin I., Unger, Christian, Andrews, Peter W.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2017
Teme:
Report
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5639211/
https://ncbi.nlm.nih.gov/pubmed/28919261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.08.008
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