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Monoubiquitination of syntaxin 3 leads to retrieval from the basolateral plasma membrane and facilitates cargo recruitment to exosomes

Syntaxin 3 (Stx3), a SNARE protein located and functioning at the apical plasma membrane of epithelial cells, is required for epithelial polarity. A fraction of Stx3 is localized to late endosomes/lysosomes, although how it traffics there and its function in these organelles is unknown. Here we repo...

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Detalles Bibliográficos
Publicado en:Mol Biol Cell
Main Authors: Giovannone, Adrian J., Reales, Elena, Bhattaram, Pallavi, Fraile-Ramos, Alberto, Weimbs, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5638587/
https://ncbi.nlm.nih.gov/pubmed/28814500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-07-0461
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