Apical targeting of syntaxin 3 is essential for epithelial cell polarity

In polarized epithelial cells, syntaxin 3 localizes to the apical plasma membrane and is involved in membrane fusion of apical trafficking pathways. We show that syntaxin 3 contains a necessary and sufficient apical targeting signal centered around a conserved FMDE motif. Mutation of any of three cr...

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Bibliografische gegevens
Hoofdauteurs: Sharma, Nikunj, Low, Seng Hui, Misra, Saurav, Pallavi, Bhattaram, Weimbs, Thomas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2006
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063918/
https://ncbi.nlm.nih.gov/pubmed/16785322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200603132
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