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Basolateral Sorting of Syntaxin 4 Is Dependent on Its N-terminal Domain and the AP1B Clathrin Adaptor, and Required for the Epithelial Cell Polarity

Generation of epithelial cell polarity requires mechanisms to sort plasma membrane proteins to the apical and basolateral domains. Sorting involves incorporation into specific vesicular carriers and subsequent fusion to the correct target membranes mediated by specific SNARE proteins. In polarized e...

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Detalhes bibliográficos
Main Authors: Reales, Elena, Sharma, Nikunj, Low, Seng Hui, Fölsch, Heike, Weimbs, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115984/
https://ncbi.nlm.nih.gov/pubmed/21698262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021181
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