טוען...
Conditional knockout of Fgf13 in murine hearts increases arrhythmia susceptibility and reveals novel ion channel modulatory roles
The intracellular fibroblast growth factors (iFGF/FHFs) bind directly to cardiac voltage gated Na(+) channels, and modulate their function. Mutations that affect iFGF/FHF-Na(+) channel interaction are associated with arrhythmia syndromes. Although suspected to modulate other ionic currents, such as...
שמור ב:
| הוצא לאור ב: | J Mol Cell Cardiol |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5637556/ https://ncbi.nlm.nih.gov/pubmed/28119060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2017.01.009 |
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