Conditional knockout of Fgf13 in murine hearts increases arrhythmia susceptibility and reveals novel ion channel modulatory roles

The intracellular fibroblast growth factors (iFGF/FHFs) bind directly to cardiac voltage gated Na(+) channels, and modulate their function. Mutations that affect iFGF/FHF-Na(+) channel interaction are associated with arrhythmia syndromes. Although suspected to modulate other ionic currents, such as...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Mol Cell Cardiol
Main Authors: Wang, Xiangchong, Tang, He, Wei, Eric Q., Wang, Zhihua, Yang, Jing, Yang, Rong, Wang, Sheng, Zhang, Yongjian, Pitt, Geoffrey S., Zhang, Hailin, Wang, Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5637556/
https://ncbi.nlm.nih.gov/pubmed/28119060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2017.01.009
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados