Identification of 76 novel B1 metallo-β-lactamases through large-scale screening of genomic and metagenomic data

BACKGROUND: Metallo-β-lactamases are bacterial enzymes that provide resistance to carbapenems, the most potent class of antibiotics. These enzymes are commonly encoded on mobile genetic elements, which, together with their broad substrate spectrum and lack of clinically useful inhibitors, make them...

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Detalhes bibliográficos
Publicado no:Microbiome
Main Authors: Berglund, Fanny, Marathe, Nachiket P., Österlund, Tobias, Bengtsson-Palme, Johan, Kotsakis, Stathis, Flach, Carl-Fredrik, Larsson, D G Joakim, Kristiansson, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5637372/
https://ncbi.nlm.nih.gov/pubmed/29020980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40168-017-0353-8
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