Identification of 76 novel B1 metallo-β-lactamases through large-scale screening of genomic and metagenomic data

BACKGROUND: Metallo-β-lactamases are bacterial enzymes that provide resistance to carbapenems, the most potent class of antibiotics. These enzymes are commonly encoded on mobile genetic elements, which, together with their broad substrate spectrum and lack of clinically useful inhibitors, make them...

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Bibliografiske detaljer
Udgivet i:Microbiome
Main Authors: Berglund, Fanny, Marathe, Nachiket P., Österlund, Tobias, Bengtsson-Palme, Johan, Kotsakis, Stathis, Flach, Carl-Fredrik, Larsson, D G Joakim, Kristiansson, Erik
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5637372/
https://ncbi.nlm.nih.gov/pubmed/29020980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40168-017-0353-8
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