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Identification of 76 novel B1 metallo-β-lactamases through large-scale screening of genomic and metagenomic data

BACKGROUND: Metallo-β-lactamases are bacterial enzymes that provide resistance to carbapenems, the most potent class of antibiotics. These enzymes are commonly encoded on mobile genetic elements, which, together with their broad substrate spectrum and lack of clinically useful inhibitors, make them...

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Detalles Bibliográficos
Publicado en:Microbiome
Main Authors: Berglund, Fanny, Marathe, Nachiket P., Österlund, Tobias, Bengtsson-Palme, Johan, Kotsakis, Stathis, Flach, Carl-Fredrik, Larsson, D G Joakim, Kristiansson, Erik
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5637372/
https://ncbi.nlm.nih.gov/pubmed/29020980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40168-017-0353-8
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