Computational discovery and functional validation of novel fluoroquinolone resistance genes in public metagenomic data sets

BACKGROUND: Fluoroquinolones are broad-spectrum antibiotics used to prevent and treat a wide range of bacterial infections. Plasmid-mediated qnr genes provide resistance to fluoroquinolones in many bacterial species and are increasingly encountered in clinical settings. Over the last decade, several...

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發表在:BMC Genomics
Main Authors: Boulund, Fredrik, Berglund, Fanny, Flach, Carl-Fredrik, Bengtsson-Palme, Johan, Marathe, Nachiket P., Larsson, DG Joakim, Kristiansson, Erik
格式: Artigo
語言:Inglês
出版: BioMed Central 2017
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581476/
https://ncbi.nlm.nih.gov/pubmed/28865446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-4064-0
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