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Murine LRBA deficiency causes CTLA-4 deficiency in Tregs without progression to immune dysregulation
Inherited mutations in lipopolysaccharide-responsive beige-like anchor (LRBA) cause a recessive human immune dysregulation syndrome with memory B-cell and antibody deficiency (common variable immunodeficiency), inflammatory bowel disease, enlarged spleen and lymph nodes, accumulation of activated T...
Enregistré dans:
| Publié dans: | Immunol Cell Biol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5636941/ https://ncbi.nlm.nih.gov/pubmed/28611475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2017.50 |
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