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Pan-cancer analysis of bi-allelic alterations in homologous recombination DNA repair genes
BRCA1 and BRCA2 are involved in homologous recombination (HR) DNA repair and are germ-line cancer pre-disposition genes that result in a syndrome of hereditary breast and ovarian cancer (HBOC). Whether germ-line or somatic alterations in these genes or other members of the HR pathway and if mono- or...
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| 發表在: | Nat Commun |
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| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5636842/ https://ncbi.nlm.nih.gov/pubmed/29021619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00921-w |
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