Matrine prevents bone loss in ovariectomized mice by inhibiting RANKL-induced osteoclastogenesis

Osteoporosis is a metabolic bone disease characterized by decreased bone density and strength due to excessive loss of bone protein and mineral content. The imbalance between osteogenesis by osteoblasts and osteoclastogenesis by osteoclasts contributes to the pathogenesis of postmenopausal osteoporo...

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Veröffentlicht in:FASEB J
Hauptverfasser: Chen, Xiao, Zhi, Xin, Pan, Panpan, Cui, Jin, Cao, Liehu, Weng, Weizong, Zhou, Qirong, Wang, Lin, Zhai, Xiao, Zhao, Qingiie, Hu, Honggang, Huang, Biaotong, Su, Jiacan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2017
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636701/
https://ncbi.nlm.nih.gov/pubmed/28739641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700316R
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