Matrine derivate MASM uncovers a novel function for ribosomal protein S5 in osteoclastogenesis and postmenopausal osteoporosis

Postmenopausal osteoporosis (POMP) is a public health problem characterized by decreased bone density and increased fracture risk. Over-activated osteoclastogenesis plays a vital role in POMP. Here we developed a novel bioactive compound MASM (M19) based on sophocarpine. Although it showed no signif...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Dis
Prif Awduron: Chen, Xiao, Zhi, Xin, Cao, Liehu, Weng, Weizong, Pan, Panpan, Hu, Honggang, Liu, Chao, Zhao, Qingjie, Zhou, Qirong, Cui, Jin, Su, Jiacan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636967/
https://ncbi.nlm.nih.gov/pubmed/28880271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.394
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg