LC-MS/MS assay for the quantitation of the ribonucleotide reductase inhibitor triapine in human plasma

The ribonucleotide reductase inhibitor and radiosensitizer triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP), NSC 663249) is clinically being evaluated via the intravenous (IV) route for the treatment of cervical and vulvar cancer in combination with primary cisplatin chemoradiatio...

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發表在:J Pharm Biomed Anal
Main Authors: Matsumoto, Julia, Kiesel, Brian F., Parise, Robert A., Guo, Jianxia, Taylor, Sarah, Huang, Marilyn, Eiseman, Julie L., Ivy, S. Percy, Kunos, Charles, Chu, Edward, Beumer, Jan H.
格式: Artigo
語言:Inglês
出版: 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636190/
https://ncbi.nlm.nih.gov/pubmed/28881312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2017.08.036
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