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LC-MS/MS assay for the quantitation of the tyrosine kinase inhibitor neratinib in human plasma

Neratinib is an orally available tyrosine kinase inhibitor targeting HER2 (ERBB2) and EGFR (ERBB). It is being clinically evaluated for the treatment of breast and other solid tumors types as a single agent or in combination with other chemotherapies. In support of several phase I/II clinical trials...

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書目詳細資料
發表在:J Pharm Biomed Anal
Main Authors: Kiesel, Brian F., Parise, Robert A., Wong, Alvin, Keyvanjah, Kiana, Jacobs, Samuel, Beumer, Jan H.
格式: Artigo
語言:Inglês
出版: 2016
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5183482/
https://ncbi.nlm.nih.gov/pubmed/27907855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2016.11.035
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