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LC-MS/MS assay for the quantitation of the tyrosine kinase inhibitor neratinib in human plasma

Neratinib is an orally available tyrosine kinase inhibitor targeting HER2 (ERBB2) and EGFR (ERBB). It is being clinically evaluated for the treatment of breast and other solid tumors types as a single agent or in combination with other chemotherapies. In support of several phase I/II clinical trials...

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Podrobná bibliografie
Vydáno v:J Pharm Biomed Anal
Hlavní autoři: Kiesel, Brian F., Parise, Robert A., Wong, Alvin, Keyvanjah, Kiana, Jacobs, Samuel, Beumer, Jan H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5183482/
https://ncbi.nlm.nih.gov/pubmed/27907855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2016.11.035
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