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LC-MS/MS assay for the quantitation of FdCyd and its metabolites FdUrd and FU in human plasma
The hypomethylating agent 5-fluoro-2′-deoxycytidine (FdCyd, NSC 48006) is being evaluated clinically both via the intravenous route and via the oral route in combination with 3,4,5,6-tetrahydrouridine (THU), a potent inhibitor of FdCyd catabolism. To determine the pharmacokinetics of FdCyd and downs...
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| Publicado no: | J Pharm Biomed Anal |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5003709/ https://ncbi.nlm.nih.gov/pubmed/27454087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2016.07.027 |
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