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Comprehensive benchmarking of SNV callers for highly admixed tumor data

Precision medicine attempts to individualize cancer therapy by matching tumor-specific genetic changes with effective targeted therapies. A crucial first step in this process is the reliable identification of cancer-relevant variants, which is considerably complicated by the impurity and heterogenei...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bohnert, Regina, Vivas, Sonia, Jansen, Gunther
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5636151/
https://ncbi.nlm.nih.gov/pubmed/29020110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186175
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